04.- 06. Mai. 2022 (ENGL) Vitamin D, HOMBURG

https://symposiumvitamindeffectoflight.jimdofree.com

1.) Vitamin D in Prevention and Therapy

on May 04 - 05, 2022

 

2.) Biologic Effects of Light

on May 05 - 06. 2022

 

Schlossberg Hotel

Homburg/ Saar, Germany

_________________________________________________________________________

Dear Participants, Colleagues and Friends!

 
  • On behalf of the scientific committee, it is a pleasure to invite you cordially to our next Joint International Symposium Vitamin D in Prevention and Therapy and Biologic Effects of Light that we will organize on May 04 - 06, 2022 in Homburg (Saar), Germany.
  • Recently, enormous scientific progress has been made on these closely related topics.
  • Results from laboratory and clinical investigations have now unravelled many of the molecular mechanisms that mediate the biologic effects both of vitamin D an optical radiation, thereby leading to promising new concepts for the prevention and treatment of cancer and many other diseases.
  • However, our increasing knowledge about the impact of vitamin D and optical radiation for human health has opened many new unresolved questions that are at present controversially discussed in the scientific community.
  • This meeting is specially designed to give scientists and clinicians an update on these topics and insights into the latest developments in these intriguing research areas.
  • To reach this goal, lectures will be held by leading experts in the field who will present "both sides of the coin".
  • Plenary and keynote lectures, as well as round table discussions and poster presentations, will give an update on carefully selected "hot topics", including vitamin D, skin cancer prevention, risks and benefits of sunscreens, UVA radiation and cellular homeostasis, photocarcinogenesis, circadian clock, and what genome wide association studies tell us about sun exposure and melanoma aetiology.
  • You are cordially invited to join this meeting.

 We hope we will see you next May in Homburg.
  • Jörg Reichrath
  • Michael Friedrich
  • Michael F. Holick
  • Thomas Vogt
_________________________________________________________________________

übersetzt:
  • Es ist mir eine Freude, Sie im Namen des wissenschaftlichen Komitees herzlich zu unserem nächsten Joint International Symposium Vitamin D in Prevention and Therapy and Biological Effects of Light einzuladen, das wir vom 04. bis 06. Mai 2022 in Homburg (Saar) veranstalten werden .
  • Bei diesen eng verwandten Themen wurden in jüngster Zeit enorme wissenschaftliche Fortschritte erzielt.
  • Ergebnisse aus Labor- und klinischen Untersuchungen haben nun viele der molekularen Mechanismen entschlüsselt, die die biologischen Wirkungen sowohl von Vitamin D als auch von optischer Strahlung vermitteln, was zu vielversprechenden neuen Konzepten für die Prävention und Behandlung von Krebs und vielen anderen Krankheiten geführt hat.
  • Unser zunehmendes Wissen über die Auswirkungen von Vitamin D und optischer Strahlung auf die menschliche Gesundheit hat jedoch viele neue ungelöste Fragen aufgeworfen, die derzeit in der wissenschaftlichen Gemeinschaft kontrovers diskutiert werden.
  • Dieses Treffen wurde speziell entwickelt, um Wissenschaftler und Kliniker über diese Themen auf dem Laufenden zu halten und Einblicke in die neuesten Entwicklungen in diesen faszinierenden Forschungsgebieten zu erhalten.
  • Um dieses Ziel zu erreichen, werden Vorträge von führenden Experten der Branche gehalten, die „beide Seiten der Medaille“ präsentieren.
  • Plenar- und Grundsatzvorträge sowie Diskussionsrunden und Posterpräsentationen geben einen Überblick über sorgfältig ausgewählte "heiße Themen", darunter Vitamin D, Hautkrebsprävention, Risiken und Vorteile von Sonnenschutzmitteln, UVA-Strahlung und zelluläre Homöostase, Photokarzinogenese, circadiane Uhr, und was uns genomweite Assoziationsstudien über Sonnenexposition und Melanom-Ätiologie sagen.
  • Sie sind herzlich eingeladen, an diesem Treffen teilzunehmen.
_________________________________________________________________________

>>> https://symposiumvitamindeffectoflight.jimdofree.com/programme/ <<<

https://symposiumvitamindeffectoflight.jimdofree.com/programme/

Welcome

Dear Participants, Colleagues and Friends,

on behalf of the scientific committee, it is a pleasure to invite you cordially to our Joint International Symposium Vitamin D in Prevention and Therapy and Biologic Effects of Light.

Increasing knowledge about the impact of vitamin D and optical radiation for human health has opened many new questions.

You are cordially invited to join this meeting.

We hope to see you soon in Homburg!

_________________________________________________________________________

Invited Speakers

  • Bernhardt, R. (Saarbrücken, Germany)
  • Bishop, T. (Leeds, UK)
  • Brenner, H. (Heidelberg, Germany)
  • Carlberg, C. (Kuopio, Finland)
  • de Grujil, F.R. (Leiden, Netherlands)
  • Emmert, S. (Rostock, Germany)
  • Frank, J. A. (Göttingen, Germany)
  • Gandini, S. (Milano, Italy)
  • Grant, W.B. (San Francisco, USA)
  • Herrmann, M. (Graz, Austria)
  • Holick, M.F. (Boston, USA)
  • Jung, N. (Homburg, Germany)
  • Kattner, L., (Saarbrücken, Germany)
  • Lammert, F. (Homburg, Germany)
  • Lindqvist, P.G. (Huddinge, Sweden)
  • Mahfoud, F. (Homburg, Germany)
  • März, W. (Mannheim, Germany)
  • Neumann, N. J. (Düsseldorf, Germany)
  • Newton-Bishop, J. (Leeds, UK)
  • Pilz, S. (Graz, Austria)
  • Rochel, N. (Illkirch, France)
  • Schöpe, J. (Homburg, Germany)
  • Slominski, A. (Birmingham, USA)
  • Smola, S. (Homburg, Germany)
  • Tanew, A. (Vienna, Austria)
  • Vieth, R. (Toronto, Canada)
  • Volmer, D. (Berlin, Germany)
  • Webb, A. (Manchester, UK)
  • Wulf, H.C. (Copenhagen, Denmark)
  • Young, A. (London, UK)
  • Zittermann, A. (Bad Oeynhausen, Germany)

Local Organizing Committee

Felix-Fernandes, T. (Homburg, Germany) Preiß, M. (Homburg, Germany)
Reichrath, J. (Homburg, Germany)
Vogt, Th. (Homburg, Germany)

Scientific Board

Bernhardt, R. (Saarbrücken, Germany)
Grant, W.B. (San Francisco, USA)
Holick, M.F. (Boston, USA)
Jung, N. (Homburg, Germany)
Preiß, M. (Homburg, Germany)
Reichrath, J. (Homburg, Germany)
Vogt, Th. (Homburg, Germany)

Place and Dates

  • The symposium is held at the Schlossberg-Hotel Homburg, Germany ( https://schlossberghotelhomburg.de/ )
  • from May 27 - 29, 2020.
  • Dead-line for abstract submission is March 15, 2020,
  • please have a look at: 
  • https://symposiumvitamindeffectoflight.jimdofree.com/

Conference Language

English

Registration

Please have a look at: https://symposiumvitamindeffectoflight.jimdofree.com/

Information and Contact

T. Felix Fernandes and M. Preiß Department of Dermatology

The Saarland University
66421 Homburg/Saar, Germany Phone: +49-6841-1623802

Fax: +49-6841-1623830

E-mail: vitamind.effectsoflight@gmail.com


_________________________________________________________________________



Download-Link Kongress-Flyer
_________________________________________________________________________

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Programm:

(PDF-Extrakt in verkürzter Fassung)

 

Joint International Symposium

Vitamin D in Prevention and Therapy and
Biologic Effects of Light

Organized by
J. Reichrath
1, M.F. Holick2, M. Friedrichand Th. VogtMay 04-06, 2022

1Dept. of Dermatology, Venerology and Allergology, The Saarland University Hospital,
Homburg/Saar, Germany;

2Dept. of Medicine/Endocrinology, Boston Medical Center, Boston, MA, USA and
3Dept. of Gynecology, Helios Clinic Krefeld, Krefeld, Germany.

PRELIMINARY PROGRAMME

Organizing Committee

M. Friedrich, Krefeld, Germany M.F. Holick, Boston, USA
J. Reichrath, Homburg, Germany Th. Vogt, Homburg, Germany

Local Organizing Committee

T. Felix Fernandes, Homburg/Saar M. Preiß, Homburg/Saar
J. Reichrath, Homburg/Saar R.Saternus, Homburg/Saar

Th. Vogt, Homburg/Saar

Scientific Board

M. Preiß, Homburg/Saar M.F. Holick, Boston
J. Reichrath, Homburg/Saar Th. Vogt, Homburg/Saar

Supported by Deutsche Forschungsgemeinschaft (DFG)

CONGRESS INFORMATION Location

The symposium is held at the Schlossberg-Hotel Homburg, Schlossberg- Höhenstraße,

66424 Homburg / Saar, GERMANY, Tel: 0049-(0)6841-6660 -
Fax: 0049-(0)-6841-62018 – Email: info@schlossberghotelhomburg.de

Congress Office

Frau Nicole Brengel
Sekretariat Professor Dr. med. Jörg Reichrath
Stellvertretender Klinikdirektor / Leitender Oberarzt
Klinik für Dermatologie, Venerologie und Allergologie
Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des
Saarlandes
Kirrbergerstraße
D-66421 Homburg / Saar
Germany
Tel.: 0049-(0)6841-1623832
E-mail: nicole.brengel@uks.eu

Desks

From Wednesday, May 4 at 7.30 AM the congress office with the following desks
will be situated during the symposium at the Schlossberg-Hotel Homburg: 
Registration/Information/Travel/Secretariat/Projection

Corona Pandemia

Please note that the official rules and regulations have to be respected. Detailled
information can be found at our home page.

Conference Language

English

Presentation

Speakers are requested to turn their presentations (power point) over to the
projectionist at least 15 minutes before the session begins.

Social Programme

The organizers invite all speakers and registered participants on Tuesday
evening (7.30 PM) to a welcome reception and on Wednesday/Thursday
evening for dinner, all at the Schlossberg hotel. For accompanying persons,
tickets for welcome reception (30 EURO/person) and dinner (50 EURO/person) can be purchased at the registration desk.

Payment

Registration fee:

Students: 50 Euro for one symposium: Vitamin D OR BEOL 75 Euro for both
symposia: Vitamin D 
AND BEOL

Other participants: 250 Euro for one symposium: Vitamin D OR BEOL 350 Euro
for both symposia: Vitamin D 
AND BEOL


Vitamin D in Prevention and Therapy

PRELIMINARY PROGRAMME

Wednesday, May 4

Registration 

Featured Lectures

Welcome address

 Opening remarks
T. Vogt (Homburg), M.F Holick (Boston), and J. Reichrath (Homburg):

I. Keynote Lecture

Chair: A.T. Slominski (Birmingham, USA)

C. Carlberg (Kuopio Finland)

M. F. Holick (Boston, USA):

Vitamin D for Human Health: History is repeating itself

 

II. Personalized Medicine and Vitamin D: Promises and pitfalls (I)

Chair: A.T. Slominski (Birmingham, USA) C. Carlberg (Kuopio Finland)
 

A.T. Slominski (Birmingham, USA)
C. Carlberg (Kuopio Finland)

An introduction to personalized medicine and vitamin D: assessing the opinion of the audience by an
interactive voting system

C. Carlberg (Kuopio, Finland):

Personalized Vitamin D Signaling

L. Kattner (Saarbrücken, Germany)

Synthesis of 13C-labelled vitamin D metabolites for their use in LC- MS/MS applications

Ben Schöttker (Heidelberg, Germany

Efficacy and safety of a personalized vitamin Dloading dose followed by 2,000 IU per day to raise
serum 25-hydroxyvitamin D in colorectal cancer patients with vitamin D insufficiency. Interim analysis of a RCT

J.T. Bittenbring (Homburg, Germany)

How to rapidly substitute vitamin D in patients with diffuse large-B-cell lymphoma

 


III. Personalized Medicine and Vitamin D: Promises and pitfalls (II) ..

Chair: A.. Zitterman (Bad Oeynhausen, Germany) H. Brenner (Heidelberg, Germany)

S. Zelzer (Graz, Austria)

Mass spectrometric determination of vitamin D metabolites in serum, a convenient tool to identify
individuals with 24-hydroxylase deficiency
.

A.T. Slominski (Birmingham, USA)

Alternative Nuclear Receptors for Vitamin D Hydroxyderivatives

 

Round Table Discussion: assessing the opinion of the audience using an interactive
voting system

Personalized medicine and vitamin D: urgent need or waste of time and resources?

(chair: A.T. Slominski (Birmingham, USA) and Winfried März (Mannheim, Germany);
podium: M. F. Holick (Boston, USA), H. Brenner (Heidelberg, Germany), S. Gandini
(Milan, Italy), C. Carlberg (Kuopio, Finland), A. Zittermann (Bad Oeynhausen, Germany).

IV Molecular Biology of Vitamin D

Chair: N. Rochel (Illkirch, France): M.A. Maestro (La Coruna, Spain)

N. Rochel (Illkirch, France):

Novel Structural Aspects of Vitamin D Signaling and Function of VDR

R. Bernhardt (Saarbrücken, Germany)

Functional and structural characterization of cholesterol-. vitamin D2- and D3-hydroxylases from
BACILLUS MEGATERIUM

M.A. Maestro (La Coruna, Spain)

Developments towards synthesis of labeled vitamin D metabolites

Dieter Steinhilber (Frankfurt, Germany)
Vitamin D and immune response: 1,25(OH)2Dregulates host defense- relevant genes by
transcript initiation and elongation

 

V Vitamin D in Prevention and Therapy (I)

Chair:A.R. Webb (Manchester, UK) S. Ramondi (Milan, Italy)

A. Zittermann (Bad Oeynhausen, Germany)

The impact of vitamin D on cardiovascular disease, and beyond

C. Diaconu (Bucharest, Romania)

Vitamin D and the heart: controversies still exist

R. Mahtani (Pune, India)

Daily oral vitamin Din the management of psoriasis: A case series.

Marcus O.W. Grimm (Homburg, Germany)

Impact of vitamin D in Alzheimer`s disease

M.F. Holick (Boston, USA),

A new insight as to how vitamin D can help reduce morbidity and mortality in covid-19 patients

S. Gandini (Milan, Italy)

Vitamin D supplementation may improve covid-19 prognosis? Evidence from a systematic review and
meta-analysis.


VI Vitamin D in Health and Disease

Chair: H. C. Wulf (Copenhagen, Denmark)

 

A. Zhu (Heidelberg, Germany).

Vitamin D binding protein, total, „non-bioavailable“, bioavailable, and free 25-hydroxyvitamin D, and
mortality in a large population-based cohort of older adults

I.M. Heerfordt (Copenhagen, Denmark)

Vitamin D status in individuals with erythropoeietic protoporphyria

A.R. Webb (Manchester, UK)

Exploring enhancement of dietary vitamin D in climates where cutaneous synthesis is
sasonally restricted

Closing Remarks: J. Reichrath, Th. Vogt

 

Thursday, May 5

 

Vitamin D in Prevention and Therapy of Skin Cancer

T. Vogt (Homburg, Germany)
Hans Christian Wulf (Copenhagen, Denmark)

Andrzej T. Slominski (Birmingham, USA)

CYP11A1-derived vitamin D hydroxyderivatives as therapeutics against skin cancer

F.R. de Gruijl (Leiden, The Netherlands)

Impacts of UV and vitamin D on skin cancer , mouse experiments

P.A. Philipsen (Copenhagen, Denmark)

High oral vitamin D intake does not protect against UVR-induced squamous cell carcinoma in
hairless mice.

J. Reichrath (Homburg, Germany)

Low vitamin D status is associated with poor clinical outcome in advanced melanoma treated with
immune checkpoint or BRAF/MEK- inhibitors: results from a pilot study

 

Keynote Lecture

M.F. Holick (Boston, USA)

The future of vitamin D: Novel therapeutic approaches for healthy , obese and malabsorption in the
era of covid-19 (

 

VII

Vitamin D Supplementation, Food Fortification: Time to act?

Chair: S. Gandini (Milan, Italy)
H. Brenner (Heidelberg, Germany)

S. Gandini (Milan, Italy)
H. Brenner (Heidelberg, Germany)

An introduction to vitamin D supplementation, food fortification : assessing the opinion of the
audience by an interactive voting system

W. März (Mannheim, Germany)

Vitamin D food fortification: Time to act

S. Kuznia (Heidelberg, Germany)

Efficacy of vitamin Dsupplementation on cancer mortality in the general population and the
prognosis of patients with cancer: A systematic review and individual patient data meta-analysis of
randomized controlled trials

F. Bellerba (Milan, Italy)

Colorectal cancer, vitamin D and microbiota: a double-blind phase II randomized trial in colorectal
cancer patients.

S. Sha (Heidelberg, Germany)1
Real world evidence for the effectiveness of vitamin D supplementation in the reduction
of total and cause specific mortality. Results from almost half a million participants of the UK Biobank cohort study

H. Brenner (Heidelberg, Germany),

Potential of vitamin D supplementation or vitamin D food fortification for preventing cancer death in
Germany


Round Table Discussion: assessing the opinion of the audience using an interactive
voting system

Vitamin D Supplementation, Food Fortification: Time to act?

(chair: Hermann Brenner (Heidelberg, Germany) and Winfried März (Mannheim,
Germany); podium: M. F. Holick (Boston, USA), A.T.

Slominski (Birmingham, USA), S. Gandini (Milan, Italy), A. Zittermann (Bad Oeynhausen,
Germany) C. Carlberg (Kuopio, Finland)

___________________________________________________________________ 

Concluding Remarks: J. Reichrath, Th. Vogt ___________________________________________________________________

Biologic Effects of Light

PRELIMINARY PROGRAMME Featured Lectures

Opening remarks
M.F. Holick (Boston), Th. Vogt and J. Reichrath (Homburg):

I Keynote Lecture

Chair:: P.G. Lindqvist (Stockholm, Sweden) H. C. Wulf (Copenhagen, Denmark)

 Donat-P. Häder (Erlangen, Germany)

Photosynthesis in plants and algae

II. Optical Radiation and Human Health (I)

Chair:: P.G. Lindqvist (Stockholm, Sweden) H. C. Wulf (Copenhagen, Denmark)

William B. Grant (San Francisco, USA)

A narrative review of observational studies of personal UVB exposure and risk of cancer

Jacqueline Rehner (Homburg, Germany)

Modulation of the skin microbiota by optical radiation

 Pelle G Lindqvist,(Stockholm, Sweden)

 

Sun exposure – Hazards and benefits

 

III. Optical Radiation and Human Health (II)

Hans Christian Wulf (Copenhagen, Denmark)

A simple procedure to determine the minimal erythema dose (MED)

Antony R Young (London, UK)
A revised action spectrum for vitamin D synthesis

Jörg Reichrath (Homburg, Germany)

Potential harmful effects associated with the use of sunscreens to prevent skin cancer –
the good, the bad and the ugly of sun prorection

Marie Christine Martens (Rostock, Germany)
Molecular pathology and clinical management of xeroderma pigmentosum – an update

 

Friday, May 6

Registration

Featured Lectures
I. Optical Radiation and Human Health (I)

 

Chair:

J. Reichrath (Homburg, Germany)

 

Andrzej T. Slominski (Birmingham, USA)

An introduction to effects of optical radiation on human health assessing the opinion of the audience
by an i
nteractive voting system

T. Vogt (Homburg, Germany) A. Tanew(Vienna,Austria:

Keynote Lecture

 

Andrzej T. Slominski (Birmingham, USA)

Urs Albrecht (Fribourg, Switzerland)

Light, the circadian clock and behavioural despair

William B. Grant (San Francisco, USA)

Solar radiation factors that affect the seasonality of diseases

On the ultraviolet B (UVB) regulation of the cutaneous and systemic immune system
 

II. UV-Radiation and Skin Cancer (2) – Promising New Concepts

Chair: P. A. Philipsen (Copenhagen, Denmark) C. Pföhler (Homburg, Germany)

 

Catharina M. Lerche (Copenhagen, Denmark)

Quantifying urinary thymine dimers bsed on LC-MS/MS

Felix Götzinger (Homburg, Germany)
Hydrochlorothiazide did not lead to phototoxic reactions and DNA damage in healthy volunteers –
the „HCTox-study“

Celina Pihl (Copenhagen, Denmark)

Nicotinamide and phytochemicals phloroglucinol and syringic acid delay UVR-induced squamous
cell carcinoma onset in hairless mice 
(Abstract No. 8)

Peter Alshede Philipsen (Copenhagen, Denmark)
High oral vitamin D intake does not protect against UV-induced squamous carcinoma in hairless mice

Hans Christian Wulf (Copenhagen, Denmark)

Removal of side effects in photodynamic therapy of actinic keratoses

Norbert J. Neumann (Düsseldorf, Germany)

Phototoxic skin reactions: an update

Adrian Tanew (Vienna, Austria)
Ultraviolet phototherapy of skin diseases – what`s vitamin D got to do with it?

Award of the Arnold Rikli Price

Florian Gruber (Vienna, Austria)
Light on the Epi-lipidome of the Skin - Oxidized Phospholipids as Messengers of Stress and Aging”

 

III. Optical radiation and malignant melanoma: what is the evidence?

Andrzej T. Slominski (Birmingham, USA) Jörg Reichrath (Homburg, Germany)

 

Frank R. de Gruijl (Leiden, The Netherlands)

Cutaneous melanoma: sheep in wolves clothing?

Sara Gandini (Milan, Italy)

Applicability of criteria for causality to sunbed use and melanoma

Jörg Reichrath (Homburg, Germany)

Melanoma risk and solarium use: still many open questions, not the time to close the debate

Round Table Discussion: assessing the opinion of the audience using an interactive
voting system

Optical Radiation and Human Health: challenge and promise

(chair: J. Reichrath (Homburg, Germany, Hermann Brenner (Heidelberg, Germany)
and Winfried März (Mannheim, Germany); podium: M. F. Holick (Boston, USA),
A.T. Slominski (Birmingham, USA), S. Gandini (Milan, Italy), A. Zittermann (Bad
Oeynhausen, Germany) C. Carlberg (Kuopio, Finland)

__________________________________________________________________ 

Concluding Remarks: J. Reichrath, M. Friedrich, Th. Vogt