Vitamin D in Prevention and Therapy

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Vitamin D in Prevention and Therapy and

Biologic Effects of Light 

Organized by
J. Reichrath1 , M.F. Holick2 , M. Friedrich3 and Th. Vogt1 June 21-23, 2017

1 Dept. of Dermatology, Venerology and Allergology, The Saarland University Hospital, Homburg/Saar, Germany;
2 Dept. of Medicine/Endocrinology, Boston Medical Center, Boston, MA, USA and
3 Dept. of Gynecology, Helios Clinic Krefeld, Krefeld, Germany.


Organizing Committee
M. Friedrich, Krefeld, Germany M.F. Holick, Boston, USA
J. Reichrath, Homburg, Germany Th. Vogt, Homburg, Germany
Local Organizing Committee
K. Heyne, Homburg/Saar
J. Reichrath, Homburg/Saar R.Saternus, Homburg/Saar C. Schiekofer, Homburg/Saar L. Schilling, Homburg/Saar Th. Vogt, Homburg/Saar
Scientific Board
K. Heyne, Homburg/Saar M.F. Holick, Boston
J. Reichrath, Homburg/Saar C. Schiekofer, Homburg/Saar Th. Vogt, Homburg/Saar 

Einladung Flyer:

Dear Colleagues!

This time it`s Homburg, again. On behalf of the scientific committee it is a pleasure to invite you to the Joint International Symposium Vitamin D in Prevention and Therapy and Biologic Effects of Light. During the past years our knowledge about the intertwisted, fascinating and pleiotropic biologic effects of vitamin D and optical radiation has exploded. These findings have lead to new concepts for the prevention and treatment of many diseases, and it is obvious that enormous progress is beeing made on this topic. T

his meeting is specifically designed to offer scientists and clinicians insights into the latest developments in this intriguing research area. The program will include keynote lectures as well as free communications and poster presentations. You are cordially invited to join this meeting.

We hope to see you soon in Homburg!



Liebe Kolleginnen und Kollegen!

Diesmal ist es (wieder) – Homburg. Es ist uns eine große Freude, Sie im  Namen des wissenschaftlichen Ausschusses zum Gemeinsamen Internationalen Symposium „Vitamin D in Prevention and Therapy and Biologic Effects of Light“ einzuladen. In den letzten Jahren sind unsere Erkenntnisse über die eng verflochtenen, faszinierenden und pleiotropen biologischen Wirkungen von Vitamin D und optischer Strahlung explodiert. Diese Ergebnisse haben neue Konzepte zur Prävention und Behandlung zahlreicher Erkrankungen zur Folge, und der enorme Fortschritt in diesem Bereich ist offensichtlich.

Dieses Treffen ist speziell darauf ausgerichtet, Wissenschaftlern und Klinikern Einblicke in die neuesten Entwicklungen in diesem Forschungsgebiet zu gewähren. Das Programm beinhaltet Hauptvorträge, freie Beiträge und Posterpräsentationen. Sie sind herzlich eingeladen, diesem Treffen beizuwohnen.

Wir hoffen, Sie bald in Homburg begrüßen zu dürfen!



Vitamin D in Prevention and Therapy

Wednesday, June 21
7.30 AM – 6.00 PM Registration
Featured Lectures

8.00 – 8.05 AM
8.05 – 8.15 AM
M. D. Menger (Dean of the Medical Faculty of Saarland University)
Welcome address
T. Vogt (Homburg), M. Friedrich (Krefeld) and J. Reichrath (Homburg):
Opening remarks

I. Historic and Future Perspectives of Vitamin D Chairpersons: F.R. De Gruijl (Leiden, The Netherlands),
R. Vieth (Toronto, Canada)
Plenary Lecture
8.15 – 9.00 AM M. F. Holick, Boston, USA :
The D-Lightful Vitamin D for Health: A Global Perspective
(Abstract No. 11) 

II. Molecular Biology of Vitamin D
Chairpersons: F.R. De Gruijl (Leiden, The Netherlands),
9.00 – 9.30 AM
9.30 – 10.00 AM
10.00 – 10.30 AM
10.30 – 11.00 PM
R. Vieth (Toronto, Canada)
C. Carlberg, Finland :
Epigenome-wide vitamin D signaling: from in vitro to in vivo
(Abstract No. 4)
J.W. Pike, Wisconsin, USA:
The Regulation of Gene Expression by 1,25-Dihydroxyvitamin D 3 in Target Cells: New Techniques, Principles and Applications. (Abstract No. 22)
N. Rochel, Strasbourg, France :
Vitamin D receptor: Structure-Function Analysis
(Abstract No. 25)
Coffee Break

III. Molecular Biology of Vitamin D: Implications for Cancer Chairpersons: J. W. Pike (Wisconsin, USA),
F. Lammert (Homburg, Germany)
11.00 – 11.30 AM U. Wissenbach, Homburg, Germany:
TRPV6 is upregulated by vitamin D 3 and expressed in several
(Abstract No. 36) 

11.30–12.00 AM
K. Römer, Homburg, Germany:
Two brothers in arms - novel interactions between the p53 tumor suppressor and vitamin D pathways
(Abstract No. 26)
F.R. De Gruijl, Leiden, The Netherlands:
Vitamin D and cancer prevention in animal models.
(Abstract No. 9)
S. Smola, Homburg, Germany:
Vitamin D and HPV-induced carcinogenesis
(Abstract No. 30)
Lunch Break
0.00 – 0.30 PM
0.30 – 1.00 PM
1.00 – 2.15 PM

IV. Vitamin D in Prevention and Therapy (I) Chairpersons: C. Zouboulis (Dessau, Germany),

2.15 – 2.45 PM
2.45 – 3.15 PM
Th. Vogt (Homburg, Germany )
J. Newton-Bishop, Leicester, UK:
Vitamin D and melanoma
(Abstract No. 20)
S.Muralidhar, Leicester, UK:
In-Silico Analyses Of Primary Melanoma Transcriptomic Data Suggest a Protective Anti-Proliferative Role of the VitaminD-VDR Signalling Axis via Effects on Mitochondrial Translation and Oxidative Phosphorylation Genes
(Abstract No. 18)
3.15 – 3.45 PM
P. Thompson, Ulster University, UK : 

Expression and modulation of genes of pharmacokinetic and genome protective relevance within enteric cells by liganded Vitamin D receptor (VDR).
(Abstract No. 32)
J. Reichrath, Homburg, Germany:
Targeting the cutaneous vitamin D endocrine system for prevention and therapy of non-melanoma skin cancer (Abstract No. 24)
Coffee Break and Poster Session V. Vitamin D in Prevention and Therapy (II)
Chairpersons: W. März (Mannheim, Germany), S. Pilz (Graz, Austria)
3.45 – 4.15 PM
4.15 – 5.00 PM
5.00 – 5.30 PM
5.30 – 6.00 PM
6.00 – 6.30 PM
F. Lammert, Homburg, Germany:
Vitamin D and Liver Disease.
(Abstract No. 15)
J. Bittenbring, Homburg, Germany:
Optimizing 25-OH-Vitamin D3 Serum Levels for Rituximab- and Obinutuzumab-mediated Antibody-dependent Cellular Cytotoxicity
(Abstract No. 2)
C. Zouboulis, Dessau, Germany:
Clinical aspects and molecular diagnostics of skin aging – Role of vitamin D
(Abstract No. 42) 

6.30 – 7.00 PM
H. C. Wulf, Copenhagen, Denmark:
Highly individual maximum serum 25(OH)D induced by UVB and its spontaneous fall in humans.
(Abstract No. 39)
7.00 PM
Thursday, June 22


VI. Vitamin D in Prevention and Therapy (III)

7.30 AM – 6.00 PM
Chairpersons: J. Newton-Bishop (Leicester, UK), S. Wagenpfeil (Homburg, Germany )
8.00 – 8.30 AM
8.30 – 9.00 AM
9.00 – 9.30 AM
H. Brenner, Heidelberg, Germany:
Vitamin D and mortality
(Abstract No. 3)
W.B. Grant, San Francisco, USA:
Vitamin D and cancer: evidence of epidemiological studies .
(Abstract No. 7)
W. März, Mannheim, Germany:
Targeting the cutaneous vitamin D endocrine system for prevention and therapy of non-melanoma skin cancer (Abstract No. 17) 

A. Zittermann, Bad Oeynhausen, Germany:
Vitamin D status/supplementation and cardiovascular disease.
(Abstract No. 41)
D. Volmer, Saarbrücken, Mannheim, Germany:
New Experimental strategies to improve the accuracy and precision during quantitative mass spectral analysis of vitamin D metabolites in biological specimens.
(Abstract No. 35)
Coffee Break

VII Vitamin D Supplementation: Present Concepts and Outlook

Chairpersons: A. Zittermann (Bad Oeynhausen, Germany), M. Friedrich (Krefeld, Germany)
9.30 – 10.00 AM
10.00 – 10.30 AM
10.30 – 11.00 AM
11.00 – 11.30 AM
11.30 – 12.00 AM
00.00 – 1.00 PM
1.00 – 1.10 PM
S. Pilz, Graz, Austria:
Vitamin D: Current guidelines and future outlook
(Abstract No. 23)
R. Vieth, Toronto, Canada:
Challenge and Promise, The Risks and Benefits of Vitamin D Supplementation and Fortification
(Abstract No. 34)

Round Table Discussion (chair: M. F. Holick): Vitamin D in prevention and therapy – challenge and promise.

(H. Brenner, C. Carlberg, F. R. de Gruijl, M. Friedrich, W. B. Grant, M. F. Holick, W. März, J. Newton-Bishop, J.W. Pike, S. Pilz, J. Reichrath, R. Vieth, Th. Vogt, A. Zittermann)

Closing Remarks: J. Reichrath, M. Friedrich, Th. Vogt 

1.10 – 2.30 PM Lunch


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